Ivan Moskowitz, M.D., Ph.D.
Principle Investigator
Associate Professor, Departments of Pediatrics, Pathology and Human Genetics
Associate Chair for Research, Department of Pediatrics
Committee on Genetics, Genomics and Systems Biology
Committee on Development, Regeneration and Stem Cell Biology
Research Assistant Professor
My interest is gene regulation in the heart and cancer - I am a computational biologist focusing on Systems Bioinformatics and translational bioinformatics. I am currently working on precisely predicting noncoding regulatory elements and developing cutting-edge data mining algorithms and tools.
I am interested in how chromosomes are organized in the nucleus and how the disorganization is related to human disease. My special interest is laminopathies, a group of disorders caused by nuclear lamina gene mutations. I employ a range of techniques from genomics to microscopy to physiological analyses of mouse hearts.
Chul Kim, Ph.D.
Postdoctoral Researcher
I have been working on stem cell biology regarding mesoderm specification. My research interests are uncovering new mechanism of lateral plate mesoderm specification and pathways important for maturation of cardiac lineages using mouse/human pluripotent stem cells in vitro.
Megan Rowton
Postdoctoral Researcher
I am investigating the role Hedgehog Signaling plays in regulating the timing of atrial septum cardiomyocyte differentiation in the embryonic Second Heart Field. Additionally, am attemptoing to determine how cell lineage decisions are made in the heterogeneous pool of Second Heart Field progenitors.
Ozanna Burnicka-Turek
Postdoctoral Researcher
My research focuses on understanding the transcriptional control in the adult cardiac conduction system. I am working on T-box transcription factor regulation of the mature ventricular conduction system (VCS). Specifically, I am interested in how alterations in the transcriptional network regulated by Tbx5 alter the functional and molecular identity of the mature VCS.
Brigitte LaForest
Postdoctoral Researcher
My research focuses on investigating the cellular and transcriptional mechanisms underlying atrial fibrillation predisposition. I am working on defining the roles of multiple trancritpion factors in adult rhythm control by integrating electrophysiology, molecular biology and genomic tools.
Ariel Rydeen
Postdoctoral Researcher
I am interested cardiac development and investigating gene regulatory networks required for second heart field development.
Jeff Steimle
Graduate Student
My work in the lab has covered two areas of interest concerning Tbx5-dependent gene regulatory networks during development. The first has focused on understanding the role of Tbx5 in the formation of the atrial septum. The second has looked more broadly at the similarities and differences of Tbx5-dependent regulation in cardiac morphogenesis and forelimb development.
Rajiv Nadadur
Graduate Student
I study gene regulatory networks of atrial arrhythmias.
Alex Guzzetta
Graduate Student
I study the mechanisms and gene regulatory networks underlying early cardiac morphogenesis. The projects I am currently working on involve 1) Hedgehog signaling's role in the allocation and development of early cardiovascular lineages and 2) Molecular decisions that dictate the earliest bifurcation of cardiac progenitor fates into the first and second heart fields. 
Sonja Lazarevic
Graduate Student
Kaitlyn Shen
I am working with Rajiv Nadadur to study the genetic regulation of cardiac conduction. We study the role of the transcription factor, Tbx5, and regulatory noncoding RNA in atrial arrhythmias.
Margaret Gadek
I work with Rajiv Nadadur to study the genetic networks underlying cardiac conduction.  We focus on noncoding RNAs, including mircoRNAs, in the context of atrial fibrillation.
Mervenaz Koska
I work with Alex Guzzetta, assisting him in his work on the role of Hedgehog signaling in gene regulatory networks for early cardiovasculogenesis.
Nikita Deng
Lab Assistant to Megan Rowton.
Jessica Jacobs-Li
Lab Assistant to Megan Rowton.
Emery Lu
Lab Assistant to Megan Rowton.
Alex Stutzman
I am working with Kohta Ikegami to study laminopathies, a group of disorders caused by nuclear lamina gene mutations. We focus on the impact of these mutations these genes on the overall organization the genome.